香港2018买马最准资料
http://www.il67.icu
Home > Products > Intermediates > Apixaban Intermediates > Apixaban intermeidate Cas 545445-44-1

Apixaban intermeidate Cas 545445-44-1

Product Description

Chemical Name: 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one

Molecular Formula: C20H25N3O3
Formula Weight: 355
CAS No.: 545445-44-1

545445-44-1
An alternate approach to Apixaban was described. The synthesis features a novel and cost-effective synthetic strategy to construct a key N-phenylvalerolactam intermediate 4 from 4-nitroaniline. In addition, the modifiedStroke Prophylaxis with Atrial Fibrillation
Indicated to reduce risk of stroke and systemic embolism associated with nonvalvular atrial fibrillation

5 mg PO BID

Postoperative Prophylaxis of DVT/PE
Indicated following hip or knee replacement surgery

Initial: Give 2.5 mg PO 12-24 hr after surgery

Duration of therapy (hip replacement): 2.5 mg PO BID for 35 days

Duration of therapy (knee replacement): 2.5 mg PO BID for 12 days

Renal impairment, including with ESRD on dialysis

Deep Vein Thrombosis: No dose adjustment recommended; clinical efficacy and safety studies did not enroll patients with ESRD on dialysis or patients with a CrCl <15 mL/min; dosing recommendations are based on pharmacokinetic and pharmacodynamic (anti-FXa activity) data in study subjects with ESRD maintained on dialysis
synthetic route avoids the use of expensive reagents and significantly improves reaction yields. As demonstrated practically, apixaban was successfully synthesized in overall good yield (35%).


Looking for ideal Apixaban Impurity B Cardiovascular Medicine Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the Apixaban Intermediate Anti-thrombotic Drug are quality guaranteed. We are China Origin Factory of Apixaban Rout of Synthesis. If you have any question, please feel free to contact us.

Product Categories : Intermediates > Apixaban Intermediates

Email to this supplier
  • *Subject:
  • *Messages:
    Your message must be between 20-8000 characters
Communicate with Supplier?Supplier
Mr. Vid Mr. Mr. Vid
What can I do for you?
Contact Supplier
香港2018买马最准资料
天下彩票 香港赛马会官方网站 中国体彩网加盟 26选5今晚有没有开奖一 河北快三一定牛基本走势电视版 精准特单双中特 2013天空彩票开奖特码 手写综合资料 韩国快乐8开奖 上海福利彩票销售点 北单在哪买2019 河南快三20191115期 彩票开奖查询结果查询 半全场胜负 青海快3开奖结